Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787933 | 0.82 | HCAR2 (0.35) | HCAR2 | |
| SCHEMBL7785903 | 0.78 | HSD17B10 (0.39) | TSHR | |
| SCHEMBL8983616 | 0.71 | — | — | |
| SCHEMBL16936162 | 0.70 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL626513 | 0.69 | SIRT3 (0.42) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL31132417 | 0.69 | SIRT3 (0.42) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL19475045 | 0.69 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL782969 | 0.69 | MEN1 (0.37) | MEN1KMT2AADORA3TSHRMC4R | |
| SCHEMBL9978366 | 0.69 | MEN1 (0.46) | MEN1KMT2AADORA3TSHRMC4R | |
| SCHEMBL9572481 | 0.68 | DYRK1A (0.43) | MEN1KMT2AADORA3TSHRMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964855-B1 | PROCESS FOR PREPARING SUBSTITUTED PYRIMIDINE DERIVATIVES | LONZA AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| EP-0964855-A1 | PROCESS FOR PREPARING SUBSTITUTED PYRIMIDINE DERIVATIVES | LONZA A.G. (CH) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998030549-A1 | PROCESS FOR PREPARING SUBSTITUTED PYRIMIDINE DERIVATIVES | LONZA AG (CH) | 1998-07-16 | — | — | WO | disclosed |