Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780833 | 0.82 | MEN1 (0.31) | HCAR2 | |
| SCHEMBL9651930 | 0.80 | HCAR2 (0.35) | HCAR2 | |
| SCHEMBL7785903 | 0.79 | HSD17B10 (0.39) | — | |
| SCHEMBL5752103 | 0.78 | P2RX3 (0.35) | HCAR2 | |
| SCHEMBL17644333 | 0.74 | MGLL (0.33) | HCAR2 | |
| SCHEMBL9654098 | 0.73 | CYP46A1 (0.43) | — | |
| SCHEMBL8983616 | 0.72 | — | — | |
| SCHEMBL8069923 | 0.72 | — | — | |
| Water SCHEMBL8084971 | 0.71 | — | — | |
| SCHEMBL11789315 | 0.69 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964855-B1 | PROCESS FOR PREPARING SUBSTITUTED PYRIMIDINE DERIVATIVES | LONZA AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| EP-0964855-A1 | PROCESS FOR PREPARING SUBSTITUTED PYRIMIDINE DERIVATIVES | LONZA A.G. (CH) | 1999-12-22 | — | — | EP | disclosed |
| WO-1998030549-A1 | PROCESS FOR PREPARING SUBSTITUTED PYRIMIDINE DERIVATIVES | LONZA AG (CH) | 1998-07-16 | — | — | WO | disclosed |