Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 8/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 8/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.43 |
| ▸ | APLNR | P35414 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780971 | 0.90 | EPHA2 (0.47) | NMUR2NMUR1EPHA2APLNRMAPK8 | |
| SCHEMBL7786086 | 0.88 | OPRM1 (0.45) | EPHA2APLNROPRM1OPRK1 | |
| SCHEMBL27508582 | 0.86 | APLNR (0.51) | NMUR2NMUR1APLNROPRM1OPRK1 | |
| SCHEMBL7780983 | 0.85 | EPHA2 (0.41) | NMUR2NMUR1EPHA2OPRM1OPRK1 | |
| SCHEMBL30716923 | 0.84 | NMUR2 (0.51) | NMUR2NMUR1APLNRMAPK8MAPK9 | |
| SCHEMBL30716922 | 0.84 | NMUR2 (0.51) | NMUR2NMUR1APLNRMAPK8MAPK9 | |
| SCHEMBL8606332 | 0.84 | OPRM1 (0.44) | EPHA2APLNROPRM1OPRK1 | |
| SCHEMBL7785522 | 0.83 | OPRM1 (0.43) | EPHA2OPRM1OPRK1 | |
| SCHEMBL29607434 | 0.83 | NMUR2 (0.57) | NMUR2NMUR1APLNRMAPK8MAPK9 | |
| SCHEMBL1163309 | 0.83 | NMUR2 (0.51) | NMUR2NMUR1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723454-B1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | GOLDSTEIN GIDEON (US) | 2001-10-31 | — | — | EP | claimed |
| EP-0723454-A4 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RES INST INC (US) | 1998-07-29 | — | — | EP | claimed |
| US-5639729-A | NERVOUS SYSTEM DISORDERS | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1997-06-17 | — | — | US | claimed |
| EP-0723454-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | Goldstein, Gideon (US) | 1996-07-31 | — | — | EP | claimed |
| WO-1995005841-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1995-03-02 | — | — | WO | claimed |
| EP-0723454-B1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | GOLDSTEIN GIDEON (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0723454-A4 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RES INST INC (US) | 1998-07-29 | — | — | EP | disclosed |
| US-5639729-A | NERVOUS SYSTEM DISORDERS | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0723454-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | Goldstein, Gideon (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995005841-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1995-03-02 | — | — | WO | disclosed |