Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 3/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | NMUR2 | Q9GZQ4 | 8/20 | 0.44 |
| ▸ | NMUR1 | Q9HB89 | 8/20 | 0.44 |
| ▸ | APLNR | P35414 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | RAMP3 | O60896 | 5/20 | 0.41 |
| ▸ | CALCR | P30988 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780965 | 0.90 | NMUR2 (0.43) | EPHA2NMUR2NMUR1APLNRMAPK8 | |
| SCHEMBL7785514 | 0.89 | EPHA2 (0.46) | EPHA2CXCR4APLNR | |
| SCHEMBL7788531 | 0.86 | CXCR4 (0.45) | EPHA2CXCR4 | |
| SCHEMBL30716922 | 0.84 | NMUR2 (0.51) | NMUR2NMUR1APLNRMAPK8MAPK9 | |
| SCHEMBL30716923 | 0.84 | NMUR2 (0.51) | NMUR2NMUR1APLNRMAPK8MAPK9 | |
| SCHEMBL27508582 | 0.83 | APLNR (0.51) | NMUR2NMUR1APLNR | |
| SCHEMBL29607434 | 0.83 | NMUR2 (0.57) | NMUR2NMUR1APLNRMAPK8MAPK9 | |
| SCHEMBL7785528 | 0.81 | OPRM1 (0.45) | EPHA2CXCR4NMUR2NMUR1APLNR | |
| SCHEMBL7789924 | 0.81 | OPRM1 (0.48) | EPHA2CXCR4NMUR2NMUR1 | |
| SCHEMBL29564518 | 0.81 | APLNR (0.47) | EPHA2NMUR2NMUR1APLNRMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723454-B1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | GOLDSTEIN GIDEON (US) | 2001-10-31 | — | — | EP | claimed |
| EP-0723454-A4 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RES INST INC (US) | 1998-07-29 | — | — | EP | claimed |
| US-5639729-A | NERVOUS SYSTEM DISORDERS | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1997-06-17 | — | — | US | claimed |
| EP-0723454-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | Goldstein, Gideon (US) | 1996-07-31 | — | — | EP | claimed |
| WO-1995005841-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1995-03-02 | — | — | WO | claimed |
| EP-0723454-B1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | GOLDSTEIN GIDEON (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0723454-A4 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RES INST INC (US) | 1998-07-29 | — | — | EP | disclosed |
| US-5639729-A | NERVOUS SYSTEM DISORDERS | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0723454-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | Goldstein, Gideon (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995005841-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1995-03-02 | — | — | WO | disclosed |