Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778696 | 0.89 | PLD1 (0.50) | PLD1CYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL7778688 | 0.88 | PLD1 (0.50) | PLD1CYP1A2CYP2D6CYP2C19HTR1A | |
| SCHEMBL8877700 | 0.83 | MAPT (0.43) | PLD1SMN1; SMN2MAPTMEN1POLB | |
| SCHEMBL7817609 | 0.81 | HTR1A (0.46) | PLD1DRD4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7781216 | 0.79 | HPGD (0.52) | PLD1DRD4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7778722 | 0.77 | KDM1A (0.50) | PLD1GAA | |
| SCHEMBL7778614 | 0.75 | POLB (0.65) | SMN1; SMN2MAPTPOLB | |
| SCHEMBL7781108 | 0.75 | PLD1 (0.53) | PLD1HTR1A | |
| SCHEMBL8875335 | 0.75 | LMNA (0.53) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7774077 | 0.74 | PLD1 (0.53) | PLD1NPC1RAB9ASMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133293-A1 | USE OF N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| EP-0775113-B1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USEFUL AS NEUROLEPTICS | BASF AG (DE) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000030639-A1 | USE OF N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-02 | — | — | WO | disclosed |
| EP-0775113-A1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USEFUL AS NEUROLEPTICS | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004245-A1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USEFUL AS NEUROLEPTICS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |