Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PLD2 | O14939 | 1/20 | 0.40 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781173 | 0.83 | PLD1 (0.47) | MAPTPOLBKMT2AMEN1PTPN1 | |
| SCHEMBL8875335 | 0.77 | LMNA (0.53) | MAPTHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL7811687 | 0.76 | CCR2 (0.46) | HPGDPOLBHTTKMT2ACCR3 | |
| SCHEMBL7778614 | 0.76 | POLB (0.65) | MAPTHPGDPOLBHTTALDH1A1 | |
| SCHEMBL7781812 | 0.76 | POLB (0.62) | MAPTHPGDPOLBHTTKMT2A | |
| SCHEMBL7781108 | 0.76 | PLD1 (0.53) | CCR3PLD2PLD1 | |
| SCHEMBL7071623 | 0.75 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7078784 | 0.74 | MCHR1 (0.45) | MAPTPOLBALDH1A1 | |
| SCHEMBL8989768 | 0.74 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL7778722 | 0.73 | KDM1A (0.50) | HPGDPLD1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616705-A | N-substituted azabicycloheptane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0740658-A1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995015312-A1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USED, FOR EXAMPLE, AS NEUROLEPTICS | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-08 | — | — | WO | disclosed |