Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197225 | 0.81 | MAPT (0.38) | PKMLMNASMN1; SMN2F2F10 | |
| SCHEMBL7187012 | 0.79 | MAPT (0.47) | PKMLMNASMN1; SMN2F2F10 | |
| SCHEMBL7194809 | 0.79 | F10 (0.43) | LMNASMN1; SMN2F2F10MAPT | |
| SCHEMBL7788182 | 0.76 | ALDH1A1 (0.43) | PKMLMNASMN1; SMN2F2F10 | |
| SCHEMBL7195684 | 0.75 | AURKA (0.44) | PKMLMNASMN1; SMN2F2F10 | |
| SCHEMBL7788773 | 0.75 | ITGB3 (0.42) | PKMLMNASMN1; SMN2F2F10 | |
| SCHEMBL13715863 | 0.74 | PKM (0.46) | PKMLMNASMN1; SMN2F2F10 | |
| SCHEMBL7788290 | 0.73 | ITGB3 (0.43) | PKMCA1CA2MAPK1MEN1 | |
| SCHEMBL7863259 | 0.73 | PKM (0.46) | PKMLMNASMN1; SMN2F2F10 | |
| SCHEMBL7193159 | 0.72 | MEN1 (0.47) | LMNASMN1; SMN2MAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |