Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 10/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL305805 | 1.00 | GRIK1 (0.58) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL28135367 | 1.00 | GRIK1 (0.58) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL305804 | 1.00 | GRIK1 (0.58) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL7781242 | 1.00 | GRIK1 (0.58) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL8099944 | 0.97 | GRIK1 (0.56) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL8092320 | 0.97 | GRIK1 (0.56) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL4860817 | 0.95 | GRIK1 (0.58) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL4860806 | 0.95 | GRIK1 (0.58) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL7204819 | 0.92 | SLC7A5 (0.56) | GRIK1SLC7A5GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL8383423 | 0.92 | SLC7A5 (0.56) | GRIK1SLC7A5GRIK2GRM1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723194-B1 | Photographic bleaching compositions and processing method using ternary iron carboxylate complexes as bleaching agents | EASTMAN KODAK CO (US) | 2001-09-26 | — | — | EP | claimed |
| US-5582958-A | USEFUL IN REHALOGENATING FERRIC CHELATE BLEACHES | EASTMAN KODAK COMPANY (US) | 1996-12-10 | — | — | US | claimed |
| EP-0723194-A1 | Photographic bleaching compositions and processing method using ternary iron carboxylate complexes as bleaching agents | EASTMAN KODAK COMPANY (US) | 1996-07-24 | — | — | EP | claimed |
| US-5521056-A | BIODEGRADATION | EASTMAN KODAK COMPANY (US) | 1996-05-28 | — | — | US | claimed |
| JP-10059912-A | — | — | None | — | — | JP | disclosed |
| WO-2024150785-A1 | RESIN COMPOSITION CONTAINING POLYALKYLENE IMINE AND/OR POLYALKYLENE IMINE DERIVATIVE | 株式会社日本触媒 | 2024-07-18 | — | — | WO | disclosed |
| CN-113677204-B | Use of protoporphyrin IX derivatives to improve plant health | 桑科能源股份有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-113880915-B | Polypeptide for repairing mucous membrane injury or skin wound and application thereof | 四川好医生攀西药业有限责任公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-112203511-B | Macrocyclic tetrapyrrole compounds, compositions and methods for increasing abiotic stress resistance of plants | 桑科能源股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20230128730-A1 | OXYGEN IMPERMEABLE PORPHYRIN PHOTOSENSITIZER FILM COMPOSITION FOR APPLICATION TO PLANTS | NUTRIEN AG SOLUTIONS (CANADA) INC (CA) | 2023-04-27 | — | — | US | disclosed |
| EP-4106524-A1 | OXYGEN IMPERMEABLE PORPHYRIN PHOTOSENSITIZER FILM COMPOSITION FOR APPLICATION TO PLANTS | Suncor Energy Inc. (CA) | 2022-12-28 | — | — | EP | disclosed |
| CN-115103593-A | Oxygen-impermeable porphyrin photosensitizer film compositions for application to plants | 森科尔能源有限公司 | 2022-09-23 | — | — | CN | disclosed |
| US-6096487-A | CYAN DYE DENSITY MAXIMIZED IN COLOR DEVELOPED SILVER HALIDE PHOTOGRAPHIC COLOR MATERIALS BY USING A MIXTURE OF A FERRIC COMPLEX OF SPECIFIED AMINOPOLYCARBOXYLIC ACIDS AND UNCOMPLEXED PYRIDINECARBOXYLIC ACID(S) IN GIVEN MOLAR RATIO | EASTMAN KODAK COMPANY (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0859276-A1 | Cyan dye recovery using ferric aminopolycarboxylic acid bleaching composition | EASTMAN KODAK COMPANY (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5753423-A | ACID SOLUTIONS OF SUCCINIC ACID, MALEIC ACID OR MALIC ACID WITH AMINOPOLYCARBOXYLIC AID, MIXING FERRIC ION, ADDING BASE TO CHANGE PH | EASTMAN KODAK COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| JP-H1059912-A | PRODUCTION OF ASPARTIC ACID DERIVATIVE | NITTO CHEM IND CO LTD | 1998-03-03 | — | — | JP | disclosed |
| US-5582958-A | USEFUL IN REHALOGENATING FERRIC CHELATE BLEACHES | EASTMAN KODAK COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0723194-A1 | Photographic bleaching compositions and processing method using ternary iron carboxylate complexes as bleaching agents | EASTMAN KODAK COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5521056-A | BIODEGRADATION | EASTMAN KODAK COMPANY (US) | 1996-05-28 | — | — | US | disclosed |
| US-5362412-A | Aminoacids or sulfonates or sulfides with acids or sulfonates | HAMPSHIRE CHEMICAL CORP. (US) | 1994-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128730-A1 | OXYGEN IMPERMEABLE PORPHYRIN PHOTOSENSITIZER FILM COMPOSITION FOR APPLICATION TO PLANTS | PPOX, STOM, GPX4 | GRIK1 3922/4885SLC7A5 2287/4885GRIK2 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.