Aspartic Acid

Aspartic Acid

SCHEMBL8092320

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nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC6A2SLC6A3

The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 10/20 0.56
SLC7A5 Q01650 1/20 0.52
GRIK2 Q13002 6/20 0.50
GRM1 Q13255 2/20 0.48
GRM2 Q14416 2/20 0.48
GRIA4 P48058 4/20 0.47
GRIK3 Q13003 4/20 0.47
GRIK5 Q16478 4/20 0.47
SLC1A3 P43003 4/20 0.46
SLC1A2 P43004 4/20 0.46
SLC1A1 P43005 3/20 0.46
GRIA2 P42262 3/20 0.46
GRIA1 P42261 2/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GSR P00390 1/20 0.46
CYP1A2 P05177 1/20 0.46
GRM5 P41594 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aspartic Acid SCHEMBL28135367 0.97 GRIK1 (0.58) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL7781242 0.97 GRIK1 (0.58) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL305805 0.97 GRIK1 (0.58) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL7781246 0.97 GRIK1 (0.58) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL305804 0.97 GRIK1 (0.58) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL8099944 0.95 GRIK1 (0.56) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL4860806 0.92 GRIK1 (0.58) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL4860817 0.92 GRIK1 (0.58) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL15401937 0.92 GRIK1 (0.54) GRIK1SLC7A5GRIK2GRM1GRM2
Aspartic Acid SCHEMBL2459027 0.92 GRIK1 (0.54) GRIK1SLC7A5GRIK2GRM1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115176047-A Composite copper component with voids 纳美仕有限公司 2022-10-11 CN claimed
CN-109400492-B Preparation method of tetrasodium aspartate diacetate 山东泰和水处理科技股份有限公司 2021-11-12 CN claimed
CN-113330611-B Copper foil, negative electrode current collector of lithium ion battery comprising same, and method for manufacturing same 纳美仕有限公司 2024-07-09 CN disclosed
CN-115176047-A Composite copper component with voids 纳美仕有限公司 2022-10-11 CN disclosed
CN-109400492-B Preparation method of tetrasodium aspartate diacetate 山东泰和水处理科技股份有限公司 2021-11-12 CN disclosed
US-6013612-A CONTAINS AMINODICARBOXYLIC ACID N,N-DIACETIC ACID SALT, (PARTICULARLY ASPARTIC ACID N,N-DIACETIC ACID SALT OR GLUTAMIC ACID N,N-DIACETIC ACID SALT) AND A GLYCOLIC ACID SALT HAVING A PH 8.5 OR HIGHER; BIODEGRADABLE SHOWA DENKO K.K. (JP) 2000-01-11 US disclosed
US-5929006-A CONTAINING AMINODICARBOXYLIC ACID N,N-DIACETIC ACID SALT, GLYCOLIC ACID SALT AND AN ALKALI METAL HYDROXIDE; BIODEGRADATION SHOWA DENKO K.K. (JP) 1999-07-27 US disclosed
EP-0913461-A1 Cleaning agent composition SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-05-06 EP disclosed