Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | PRNP | P04156 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | OGG1 | O15527 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.46 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878607 | 0.90 | LMNA (0.56) | LMNARXFP1PRNPNPSR1RAB9A | |
| SCHEMBL8876128 | 0.82 | LMNA (0.58) | LMNARXFP1PRNPRAB9AOGG1 | |
| SCHEMBL8875335 | 0.78 | LMNA (0.53) | LMNARXFP1RAB9AOGG1NPC1 | |
| SCHEMBL7781230 | 0.76 | CD274 (0.56) | DRD2DRD3 | |
| SCHEMBL7078781 | 0.76 | LMNA (0.41) | LMNARXFP1PRNPNPSR1RAB9A | |
| SCHEMBL10148327 | 0.71 | OGG1 (0.71) | LMNARXFP1PRNPRAB9AOGG1 | |
| SCHEMBL7774100 | 0.70 | F10 (0.52) | HPGD | |
| SCHEMBL16562249 | 0.70 | MAPT (0.76) | RXFP1RAB9AOGG1NPC1KMT2A | |
| SCHEMBL15931659 | 0.69 | CA1 (0.74) | LMNARXFP1PRNPRAB9AOGG1 | |
| SCHEMBL11086844 | 0.69 | SMN1; SMN2 (0.66) | LMNARXFP1RAB9AOGG1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133293-A1 | USE OF N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| EP-0731802-B1 | N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES AS NEUROLEPTICS ETC. | BASF AG (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-2000030639-A1 | USE OF N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-02 | — | — | WO | disclosed |