Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876217 | 0.80 | MAPK1 (0.45) | F10MAPK1HPGDTSHR | |
| SCHEMBL8878672 | 0.79 | MAPK1 (0.43) | F10MAPK1HPGDTSHR | |
| SCHEMBL8877166 | 0.78 | MAPK1 (0.41) | F10MAPK1HPGDTSHR | |
| SCHEMBL8576249 | 0.77 | F10 (0.39) | F10MAPK1HPGDTSHR | |
| SCHEMBL7781841 | 0.70 | LMNA (0.61) | HPGD | |
| SCHEMBL8135623 | 0.70 | ALDH1A1 (0.55) | — | |
| SCHEMBL5630030 | 0.70 | MAPK1 (0.63) | F10MAPK1HPGDTSHRF2 | |
| SCHEMBL24177659 | 0.68 | F10 (1.00) | F10F2 | |
| SCHEMBL77589 | 0.68 | F10 (1.00) | F10F2 | |
| SCHEMBL13698655 | 0.68 | F10 (1.00) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133293-A1 | USE OF N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000030639-A1 | USE OF N-SUBSTITUTED AZABICYCLOALKANE DERIVATIVES FOR TREATING DISEASES OF THE CENTRAL NERVOUS SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-02 | — | — | WO | disclosed |