Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787171 | 0.91 | HSD11B1 (0.37) | HSD11B1USP2LMNAKDRELANE | |
| SCHEMBL6542004 | 0.72 | HSD11B1 (0.45) | HSD11B1USP2LMNAKDRELANE | |
| SCHEMBL6542587 | 0.72 | HSD11B1 (0.45) | HSD11B1USP2LMNAELANEPTGS1 | |
| SCHEMBL6542415 | 0.72 | EDNRA (0.42) | HSD11B1USP2LMNAKDRPTGS1 | |
| SCHEMBL6542734 | 0.67 | EDNRA (0.40) | HSD11B1USP2LMNAKDREDNRA | |
| SCHEMBL6542406 | 0.67 | HSD11B1 (0.51) | HSD11B1USP2LMNAKDRELANE | |
| SCHEMBL7789463 | 0.65 | CA9 (0.40) | LMNAELANEKDM4ECYP2D6 | |
| SCHEMBL6542661 | 0.62 | USP2 (0.47) | HSD11B1USP2LMNAKDRPTGS1 | |
| SCHEMBL6541854 | 0.60 | EDNRA (0.49) | PTGS2EDNRAKDM4E | |
| SCHEMBL6542493 | 0.59 | LMNA (0.56) | HSD11B1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252070-B1 | REACTING ARYL BROMIDE WITH BUTYLLITHIUM AND ZINC BROMIDE TO GIVE ARYL ZINC BROMIDE; REACTING WITH CORRESPONDING BENZOTHIAZINE COMPOUND | WARNER-LAMBERT COMPANY | 2001-06-26 | — | — | US | disclosed |