Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CEL | P19835 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | PARL | Q9H300 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787171 | 0.76 | HSD11B1 (0.37) | LMNAHPGDALDH1A1ELANEPARL | |
| SCHEMBL6542403 | 0.70 | LMNA (0.65) | CA9CA2LMNARAB9AELANE | |
| SCHEMBL6903338 | 0.64 | HPGD (0.58) | CA9CA2LMNARAB9AHPGD | |
| SCHEMBL30367636 | 0.64 | HPGD (0.58) | CA9CA2LMNARAB9AHPGD | |
| SCHEMBL10642924 | 0.63 | ELANE (0.55) | CA9CA2LMNAHPGDELANE | |
| Hydrogen Sulfide SCHEMBL29165723 | 0.62 | HPGD (0.57) | CA9CA2LMNARAB9AHPGD | |
| SCHEMBL5370319 | 0.62 | ALDH1A1 (0.35) | LMNAHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL4986865 | 0.62 | SMN1; SMN2 (0.36) | LMNAALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL2473331 | 0.62 | KMT2A (0.35) | HPGDALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL6541543 | 0.62 | LMNA (0.52) | CA9CA2LMNARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252070-B1 | REACTING ARYL BROMIDE WITH BUTYLLITHIUM AND ZINC BROMIDE TO GIVE ARYL ZINC BROMIDE; REACTING WITH CORRESPONDING BENZOTHIAZINE COMPOUND | WARNER-LAMBERT COMPANY | 2001-06-26 | — | — | US | disclosed |