Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27539616 | 0.98 | LMNA (0.56) | LMNAHSD17B10MAPTPOLBPKM | |
| Hydrochloric Acid SCHEMBL2327786 | 0.98 | LMNA (0.56) | LMNAHSD17B10MAPTPOLBPKM | |
| SCHEMBL380364 | 0.83 | HSD17B10 (0.56) | LMNAHSD17B10MAPTCYP2C9SMN1; SMN2 | |
| SCHEMBL7781973 | 0.82 | HSD17B10 (0.50) | LMNAHSD17B10MAPTPOLBCYP2C9 | |
| SCHEMBL269329 | 0.82 | LMNA (0.80) | LMNAHSD17B10MAPTPOLBPKM | |
| SCHEMBL2625475 | 0.80 | ELANE (0.60) | LMNAHSD17B10CYP2C9SMN1; SMN2ELANE | |
| SCHEMBL18727667 | 0.80 | HSD17B10 (0.58) | LMNAHSD17B10CYP2C9SMN1; SMN2CYP1A2 | |
| Lithium SCHEMBL30522746 | 0.79 | LMNA (0.76) | LMNAHSD17B10MAPTPOLBPKM | |
| SCHEMBL14760365 | 0.79 | LMNA (0.76) | LMNAHSD17B10MAPTPOLBPKM | |
| SCHEMBL7268906 | 0.79 | ELANE (0.54) | LMNAHSD17B10MAPTPOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025243208-A2 | PROCESS FOR THE PREPARATION AND/OR PURIFICATION OF POLYETHYLENE GLYCOL AND ITS DERIVATIVES, OBTAINED PRODUCT AND USES THEREOF | HOVIONE - FARMACIÊNCIA, SA (PT) | 2025-11-27 | — | — | WO | claimed |
| CN-114163456-B | Phenothiazine coumarin-based pyridine salt compound and preparation and application thereof | 西南医科大学附属医院 | 2023-08-22 | — | — | CN | claimed |
| CN-105130886-A | Preparation method for 4-fluoro-3-methyl-methyl pyridine-2-carboxylate | UNIV HENAN NORMAL | 2015-12-09 | — | — | CN | claimed |
| CN-102199120-A | Method for synthesizing 2,2'-bipyridine-4,4'-dicarboxylic acid | UNIV LIAOCHENG | 2011-09-28 | — | — | CN | claimed |
| CN-101709472-A | Preparation method of substituted pyridine carbonylhydrazone metal corrosion inhibitor | UNIV GUILIN TECH GUT | 2010-05-19 | — | — | CN | claimed |
| WO-2025243208-A2 | PROCESS FOR THE PREPARATION AND/OR PURIFICATION OF POLYETHYLENE GLYCOL AND ITS DERIVATIVES, OBTAINED PRODUCT AND USES THEREOF | HOVIONE - FARMACIÊNCIA, SA (PT) | 2025-11-27 | — | — | WO | disclosed |
| US-11834416-B2 | Cleavable agents | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
| US-11834416-B2 | Cleavable agents | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
| CN-110312533-B | Prodrugs of cytotoxic active agents having enzymatically cleavable groups | 拜耳公司 | 2023-11-03 | — | — | CN | disclosed |
| EP-3647311-B1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO LTD (CN) | 2023-11-01 | — | — | EP | disclosed |
| CN-114163456-B | Phenothiazine coumarin-based pyridine salt compound and preparation and application thereof | 西南医科大学附属医院 | 2023-08-22 | — | — | CN | disclosed |
| US-20230202981-A1 | NOVEL SMALL MOLECULES FOR TARGETED DEGRADATION OF UNTARGETABLE KRAS IN CANCER THERAPY | PILLAI UNIVERSAL LLC | 2023-06-29 | — | — | US | disclosed |
| US-4510138-A | 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]cephalosporin derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-09 | — | — | US | disclosed |
| US-4349552-A | TREATMENT OF CANCER | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-09-14 | — | — | US | disclosed |
| EP-0010941-B1 | 5-FLUOROURACIL DERIVATIVES, PREPARATION THEREOF AND THEIR PHARMACEUTICAL COMPOSITIONS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-12 | — | — | EP | disclosed |
| US-4278671-A | ANTIBIOTICS, BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-14 | — | — | US | disclosed |
| EP-0010941-A1 | 5-Fluorouracil derivatives, preparation thereof and their pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-05-14 | — | — | EP | disclosed |
| US-4182866-A | CEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-01-08 | — | — | US | disclosed |
| US-4145540-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4011214-A | 3-(MORPHOLINOALKOXYIMINOMETHYL)CEPHEM COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202981-A1 | NOVEL SMALL MOLECULES FOR TARGETED DEGRADATION OF UNTARGETABLE KRAS IN CANCER THERAPY | KRAS, HRAS, NRAS | LMNA 4288/4885HSD17B10 2892/4885MAPT 1580/4885 |
| US-11834416-B2 | Cleavable agents | LGMN, CTSL, GZMB | LMNA 174/4885HSD17B10 3457/4885MAPT 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.