Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976439 | 1.00 | LMNA (0.48) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL6976444 | 1.00 | LMNA (0.48) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL4960147 | 0.91 | LMNA (0.45) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL5844958 | 0.91 | LMNA (0.46) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL1021389 | 0.91 | LMNA (0.46) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL11097537 | 0.90 | LMNA (0.48) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL4961338 | 0.90 | LMNA (0.47) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL4961003 | 0.90 | LMNA (0.46) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL6971100 | 0.90 | CA2 (0.54) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL4964470 | 0.90 | LMNA (0.46) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841334-B1 | PROCESS FOR PRODUCING 1,4-BENZODIOXANE DERIVATIVES | DAISO CO LTD (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-5780650-A | Process for preparation of 1,4-benzodioxane derivative | DAISO CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0841334-A1 | PROCESS FOR PRODUCING 1,4-BENZODIOXANE DERIVATIVES | DAISO CO., LTD. (JP) | 1998-05-13 | — | — | EP | disclosed |