Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781954 | 0.91 | CA2 (0.53) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL6976439 | 0.90 | LMNA (0.48) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL7782073 | 0.90 | LMNA (0.48) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL6976444 | 0.90 | LMNA (0.48) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL9372518 | 0.90 | LMNA (0.46) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL440397 | 0.86 | LMNA (0.64) | LMNASMN1; SMN2CA2ALDH1A1MAPK1 | |
| SCHEMBL5845241 | 0.86 | LMNA (0.64) | LMNASMN1; SMN2CA2ALDH1A1MAPK1 | |
| SCHEMBL567428 | 0.86 | LMNA (0.64) | LMNASMN1; SMN2CA2ALDH1A1MAPK1 | |
| SCHEMBL11098694 | 0.85 | LMNA (0.43) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 | |
| SCHEMBL11099885 | 0.85 | ALDH1A1 (0.42) | LMNASMN1; SMN2CA2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470989-A | Neuroleptic n-oxacyclyl-alkylpiperidine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |