SCHEMBL778219

SCHEMBL778219

O=S(=O)(c1cccc(F)c1F)c1cccc(F)c1F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.56
PTGES2 Q9H7Z7 2/20 0.49
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
BCHE P06276 1/20 0.43
GAA P10253 1/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
PKM P14618 1/20 0.39
PKLR P30613 1/20 0.39
NAMPT P43490 1/20 0.38
HSD11B1 P28845 1/20 0.36
CNR2 P34972 1/20 0.36
IKBKB O14920 1/20 0.35
KAT6A Q92794 1/20 0.35
SGK1 O00141 1/20 0.35
ALPL P05186 1/20 0.34
ALPI P09923 1/20 0.34
ALPG P10696 1/20 0.34
DNMT1 P26358 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29860559 1.00 AKR1B1 (0.56) AKR1B1PTGES2CES2CES1BCHE
SCHEMBL545481 0.85 HTR6 (0.52) AKR1B1PTGES2GAAKMT2ANAMPT
SCHEMBL29141546 0.83 PTGES2 (0.47) AKR1B1PTGES2CES2CES1BCHE
SCHEMBL2049796 0.83 PTGES2 (0.47) AKR1B1PTGES2CES2CES1BCHE
SCHEMBL28510869 0.82 AKR1B1 (0.46) AKR1B1PTGES2GAAKMT2APKM
SCHEMBL789494 0.81 PTGES2 (0.64) AKR1B1PTGES2
SCHEMBL30307782 0.81 PTGES2 (0.64) AKR1B1PTGES2
SCHEMBL6871520 0.81 PTGES2 (0.46) AKR1B1PTGES2CES2CES1BCHE
SCHEMBL229902 0.81 PTGES2 (0.46) AKR1B1PTGES2CES2CES1BCHE
SCHEMBL29543283 0.81 PTGES2 (0.46) AKR1B1PTGES2CES2CES1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019942-A Protective film adhesive tape for flexible OLED support 宁波永恒新材料科技有限公司 2024-11-26 CN disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
CN-117489753-B Toothed synchronous belt 宁波伏龙同步带有限公司 2024-05-17 CN disclosed
CN-116655328-B Seepage-proofing and crack-proofing concrete and preparation method thereof 湖南省勘测设计院有限公司 2024-04-12 CN disclosed
CN-117489753-A Toothed synchronous belt 宁波伏龙同步带有限公司 2024-02-02 CN disclosed
CN-116655328-A Seepage-proofing and crack-proofing concrete and preparation method thereof 湖南省勘测设计院有限公司 2023-08-29 CN disclosed
CN-113372556-B Polyarylether sulfone copolymer with main chain containing platinum aromatic alkyne groups and preparation method thereof 吉林大学 2022-09-23 CN disclosed
CN-112574076-B Preparation method of difluoromethyl sulfone compound 中国科学院上海有机化学研究所 2022-08-09 CN disclosed
CN-109642388-B Surface-modified nanofiber, electrolyte membrane, method for producing electrolyte membrane, membrane electrode assembly, and solid polymer fuel cell 公立大学法人首都大学东京 2022-07-08 CN disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
EP-1247142-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS COMPRISING POLYARYL ETHERS Lexmark International, Inc. (US) 2002-10-09 EP disclosed
US-6350553-B2 CHARGE TRANSFER LAYER; CHARGE GENERATING LAYER LEXMARK INTERNATIONAL, INC. 2002-02-26 US disclosed
US-20010023047-A1 Electrophotographic photoconductors comprising polyaryl ethers LEXMARK INTERNATIONAL, INC. 2001-09-20 US disclosed
WO-2001051995-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTORS COMPRISING POLYARYL ETHERS LEXMARK INTERNATIONAL, INC. (US) 2001-07-19 WO disclosed
US-6232025-B1 CHARGE TRANSFER AND CHARGE GENERATING LAYERS LEXMARK INTERNATIONAL, INC. 2001-05-15 US disclosed
US-5442029-A Methods of preparing polymeric ketones THE CENTER FOR INNOVATIVE TECHNOLOGY (US) 1995-08-15 US disclosed
US-5344914-A Commercially valuable polymeric ketones and method of preparing same THE CENTER FOR INNOVATIVE TECHNOLOGY* (US) 1994-09-06 US disclosed
US-4774311-A FLUORIDE CATALYSTS AMOCO CORPORATION (US) 1988-09-27 US disclosed
EP-0085185-B1 INTEGRATED PROCESS FOR THE PREPARATION OF SUBSTANTIALLY LINEAR HIGH MOLECULAR WEIGHT THERMOPLASTIC POLYMERS FROM ARYL POLYHALIDE MONOMERS AMOCO CORPORATION (US) 1987-05-20 EP disclosed
EP-0211693-A1 Preparation of poly(aryl ether ketones) AMOCO CORPORATION (US) 1987-02-25 EP disclosed