SCHEMBL545481

SCHEMBL545481

O=S(=O)(c1ccccc1)c1cccc(F)c1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.52
KMT2A Q03164 1/20 0.50
AKR1B1 P15121 1/20 0.49
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA13 Q8N1Q1 1/20 0.47
PTGES2 Q9H7Z7 1/20 0.46
HSD11B1 P28845 1/20 0.45
KAT6A Q92794 1/20 0.44
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
NAMPT P43490 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
GFER P55789 1/20 0.42
CNR2 P34972 1/20 0.41
HTR2C P28335 1/20 0.40
HTR2B P41595 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776706 0.85 HTR6 (0.57) HTR6KMT2AAKR1B1CA12CA1
SCHEMBL778219 0.85 AKR1B1 (0.56) KMT2AAKR1B1PTGES2HSD11B1KAT6A
SCHEMBL29860559 0.85 AKR1B1 (0.56) KMT2AAKR1B1PTGES2HSD11B1KAT6A
SCHEMBL17181361 0.81 HSD11B1 (0.50) HTR6KMT2ACA12CA1CA2
SCHEMBL28570189 0.78 NPSR1 (0.46) HTR6CA1CA2KAT6ATSHR
SCHEMBL3974600 0.78 TSHR (0.50) HTR6KMT2ACA12CA1CA2
SCHEMBL8080841 0.78 HTR6 (0.72) HTR6KMT2ACA12CA1CA2
SCHEMBL3420592 0.75 HSD11B1 (0.52) HTR6KMT2ACA12CA1CA2
SCHEMBL29141546 0.74 PTGES2 (0.47) AKR1B1PTGES2KAT6A
SCHEMBL2049796 0.74 PTGES2 (0.47) AKR1B1PTGES2KAT6A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 854 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240200-A Low-dielectric fluorine-containing polyarylether resin and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-06-25 CN claimed
CN-118234782-A Polyether copolymers based on glycol sugar alcohols 巴斯夫欧洲公司 2024-06-21 CN claimed
CN-118185012-A Polypropylene-based polyether sulfone polymer, preparation method thereof, preparation method and application of modified bismaleimide resin 中国科学院大连化学物理研究所 2024-06-14 CN claimed
EP-4377378-A1 POLYARYLETHER COPOLYMERS BASED ON DIOLS SUGAR ALCOHOLS BASF SE (DE) 2024-06-05 EP claimed
CN-117681517-A Flame-retardant composite non-woven fabric and preparation method thereof 扬州丽铂环保材料有限公司 2024-03-12 CN claimed
CN-115490899-B Proton exchange membrane 中国科学院福建物质结构研究所 2024-02-23 CN claimed
CN-117181316-A Preparation method of monovalent anion selective solvent-resistant ion exchange membrane 浙江工业大学 2023-12-08 CN claimed
CN-117143495-A Epoxy resin anticorrosive paint and preparation method thereof 吉林大学 2023-12-01 CN claimed
CN-117004024-A Amino polyarylether epoxy curing agent and preparation method thereof 吉林大学 2023-11-07 CN claimed
WO-2023139134-A1 FUNCTIONALIZED POLY(ARYL ETHER SULFONES) COPOLYMERS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-07-27 WO claimed
CN-1673254-A Serial electrically active polyaryl ether ketone polymers and their prepn process UNIV JILIN (CN) 2005-09-28 CN claimed
CN-1195004-C Sulfonated poly phenyl thioether ketone-like ionomer and its preparation method UNIV SHANGHAI JIAOTONG (CN) 2005-03-30 CN claimed
CN-1597737-A Polyether thiosulphone copolymer and its preparation method UNIV SICHUAN (CN) 2005-03-23 CN claimed
CN-1594374-A Chiral comb-shape polymer and its preparation process UNIV JILIN (CN) 2005-03-16 CN claimed
CN-1556131-A Chiral polyether ketone (sulphone) seres polymer and preparation 吉林大学 2004-12-22 CN claimed
CN-1410473-A Sulfonated poly phenyl thioether ketone-like ionomer and its preparation method UNIV SHANGHAI JIAOTONG (CN) 2003-04-16 CN claimed
CN-1058729-C Polyaryl ether nitrile and producing process thereof UNIV SICHUAN UNITED (CN) 2000-11-22 CN claimed
CN-1166507-A Aromatic ether polymer with ketone group and side chain and its preparation UNIV SICHUAN UNION (CN) 1997-12-03 CN claimed
CN-1143652-A Method for preparing polyarylene sulfide with high molecular and high toughness UNIV SICHUAN UNION (CN) 1997-02-26 CN claimed
CN-1124745-A Polyaryl ether nitrile and producing process thereof UNIV SICHUAN UNITED (CN) 1996-06-19 CN claimed