Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RARB | P10826 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | ACR | P10323 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665942 | 1.00 | THRB (0.58) | THRBMAPTSMN1; SMN2RARBPLK1 | |
| SCHEMBL7951967 | 1.00 | THRB (0.58) | THRBMAPTSMN1; SMN2RARBPLK1 | |
| SCHEMBL7210214 | 1.00 | THRB (0.58) | THRBMAPTSMN1; SMN2RARBPLK1 | |
| SCHEMBL5665862 | 0.97 | THRB (0.63) | THRBMAPTSMN1; SMN2RARBPLK1 | |
| SCHEMBL11699664 | 0.97 | MAPT (0.55) | THRBMAPTSMN1; SMN2RARBPLK1 | |
| SCHEMBL5666123 | 0.97 | THRB (0.63) | THRBMAPTSMN1; SMN2RARBPLK1 | |
| SCHEMBL11695074 | 0.97 | MAPT (0.55) | THRBMAPTSMN1; SMN2RARBPLK1 | |
| SCHEMBL9511143 | 0.95 | THRB (0.62) | THRBMAPTSMN1; SMN2RARBTHRA | |
| SCHEMBL11547222 | 0.95 | RARB (0.64) | THRBMAPTSMN1; SMN2RARBPLK1 | |
| SCHEMBL11584932 | 0.95 | MAPT (0.54) | THRBMAPTSMN1; SMN2RARBPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071618-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-8067068-B2 | Liquid crystal compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-29 | — | — | US | disclosed |
| US-20100308265-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100308265-A1 | LIQUID CRYSTAL COMPOSITIONS | CNOT9, AQP3, AQP1 | THRB 4866/4885MAPT 23/4885SMN1; SMN2 4591/4885 |
| US-20120071618-A1 | LIQUID CRYSTAL COMPOSITIONS | CNOT9, AQP3, AQP1 | THRB 4866/4885MAPT 23/4885SMN1; SMN2 4591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.