Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.45 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.45 |
| ▸ | PRKACA | P17612 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | PRKX | P51817 | 2/20 | 0.45 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782237 | 1.00 | CAPN1 (0.49) | CAPN1LMNAMAPTROCK2ROCK1 | |
| SCHEMBL7782209 | 0.83 | CAPN1 (0.53) | CAPN1ROCK2ROCK1MAPK1RPS6KA5 | |
| SCHEMBL7782200 | 0.83 | CAPN1 (0.53) | CAPN1ROCK2ROCK1MAPK1RPS6KA5 | |
| SCHEMBL7791345 | 0.82 | CAPN1 (0.70) | CAPN1ROCK2ROCK1MAPK1RPS6KA5 | |
| SCHEMBL7380790 | 0.80 | LMNA (0.52) | LMNAMAPTROCK2ROCK1MAPK1 | |
| SCHEMBL7789861 | 0.80 | LMNA (0.52) | LMNAMAPTROCK2ROCK1MAPK1 | |
| SCHEMBL7790083 | 0.80 | CAPN1 (0.49) | CAPN1ROCK2ROCK1MAPK1RPS6KA5 | |
| SCHEMBL7382779 | 0.77 | ALDH1A1 (0.64) | LMNAMAPTROCK2ROCK1MAPK1 | |
| SCHEMBL7786734 | 0.77 | NPC1 (0.70) | LMNAMAPTROCK2ROCK1MAPK1 | |
| SCHEMBL7381190 | 0.77 | NPC1 (0.70) | LMNAMAPTROCK2ROCK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |