Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.46 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | PRKX | P51817 | 2/20 | 0.46 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789861 | 1.00 | LMNA (0.52) | LMNASMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL7383243 | 0.81 | MAPK1 (0.51) | NPC1RAB9AMAPK1CYP3A4KMT2A | |
| SCHEMBL7376752 | 0.81 | MAPK1 (0.51) | NPC1RAB9AMAPK1CYP3A4KMT2A | |
| SCHEMBL7382779 | 0.81 | ALDH1A1 (0.64) | LMNASMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL7786734 | 0.81 | NPC1 (0.70) | LMNASMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL7381190 | 0.81 | NPC1 (0.70) | LMNASMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL7782237 | 0.80 | CAPN1 (0.49) | LMNASMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL7782235 | 0.80 | CAPN1 (0.49) | LMNASMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL29018285 | 0.78 | CTSD (0.55) | LMNASMN1; SMN2MAPK1CYP3A4KMT2A | |
| SCHEMBL29018283 | 0.78 | CTSD (0.55) | LMNASMN1; SMN2MAPK1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| EP-0944584-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023581-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |