SCHEMBL7782277

SCHEMBL7782277

C=CC(=O)C(O)COc1ccc(C=O)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 8/20 0.42
MAPT P10636 3/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
ALDH1A3 P47895 1/20 0.40
POLB P06746 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PARP10 Q53GL7 1/20 0.39
PARP3 Q9Y6F1 1/20 0.39
CYP2A6 P11509 1/20 0.39
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
KDM4E B2RXH2 1/20 0.39
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694902 0.79 ALDH1A1 (0.62) KMT2AALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL18990487 0.77 ALDH1A1 (0.44) ALDH1A1MAPTLMNASMN1; SMN2HPGD
SCHEMBL18990490 0.77 ALDH1A1 (0.44) ALDH1A1MAPTLMNASMN1; SMN2HPGD
SCHEMBL11117361 0.76 PTPN7 (0.53) KMT2AALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL1931817 0.76 LMNA (0.58) KMT2AALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL3595449 0.76 LMNA (0.58) KMT2AALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL1931139 0.75 ALDH1A1 (0.46) KMT2AALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL17070011 0.75 ALDH1A1 (0.50) KMT2AALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL12353251 0.75 TSHR (0.46) KMT2AALDH1A1MAPTLMNASMN1; SMN2
SCHEMBL4142480 0.75 ADRB2 (0.44) ALDH1A1MAPTLMNAPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885408-B1 A SCREEN PRINTING STENCIL SERICOL LTD (GB) 2001-10-17 EP disclosed
US-5994033-A GRAFT POLYMER SERICOL LIMITED (GB) 1999-11-30 US disclosed
EP-0885408-A1 A SCREEN PRINTING STENCIL SERICOL LIMITED (GB) 1998-12-23 EP disclosed
WO-1997033202-A1 A SCREEN PRINTING STENCIL SERICOL LIMITED (GB) 1997-09-12 WO disclosed