Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6521398 | 0.89 | KDM4E (0.32) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| SCHEMBL7050763 | 0.87 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL27617899 | 0.85 | ALDH1A1 (0.42) | — | |
| Pyridine SCHEMBL4314572 | 0.82 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL30041159 | 0.77 | HRH3 (0.38) | — | |
| SCHEMBL7053946 | 0.76 | CYP19A1 (0.32) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL1453949 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| Lithium SCHEMBL29644507 | 0.74 | CYP19A1 (0.31) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7642643 | 0.74 | CYP19A1 (0.31) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6719841 | 0.74 | DRD2 (0.39) | CYP11B1CYP11B2HTR2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722950-B1 | Process for the preparation of bridged metallocenes | BASELL TECHNOLOGY CO BV (NL) | 2001-09-12 | — | — | EP | claimed |
| US-5968863-A | REACTION OF LIGAND WITH DOUBLE ANION FOR POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1999-10-19 | — | — | US | claimed |
| EP-0722950-A1 | Process for the preparation of bridged metallocenes | Montell Technology Company bv (NL) | 1996-07-24 | — | — | EP | claimed |
| EP-0722950-B1 | Process for the preparation of bridged metallocenes | BASELL TECHNOLOGY CO BV (NL) | 2001-09-12 | — | — | EP | disclosed |
| US-5968863-A | REACTION OF LIGAND WITH DOUBLE ANION FOR POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1999-10-19 | — | — | US | disclosed |
| EP-0722950-A1 | Process for the preparation of bridged metallocenes | Montell Technology Company bv (NL) | 1996-07-24 | — | — | EP | disclosed |