Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CASP9 | P55211 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775452 | 0.91 | CTRB1 (0.52) | CTRB1ELANECASP1CASP3CASP7 | |
| SCHEMBL8717314 | 0.86 | CTRB1 (0.52) | CTRB1CYP3A4TSHRCYP1A2CYP2D6 | |
| SCHEMBL7455452 | 0.86 | CTRB1 (0.54) | CTRB1CYP3A4TSHRCYP1A2CYP2D6 | |
| SCHEMBL7455442 | 0.86 | CTRB1 (0.54) | CTRB1CYP3A4TSHRCYP1A2CYP2D6 | |
| SCHEMBL7780900 | 0.86 | CTRB1 (0.54) | CTRB1CYP3A4TSHRCYP1A2CYP2D6 | |
| SCHEMBL7780890 | 0.85 | CTRB1 (0.46) | CTRB1ELANECYP3A4TSHRCYP1A2 | |
| SCHEMBL7775756 | 0.84 | CTRB1 (0.46) | CTRB1CYP3A4TSHRCYP1A2CYP2D6 | |
| SCHEMBL7782474 | 0.84 | SGMS2 (0.54) | CTRB1CYP3A4TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7780888 | 0.83 | SIRT2 (0.52) | ALDH1A1KCNA5 | |
| SCHEMBL2435512 | 0.81 | CTRB1 (0.76) | CTRB1CYP3A4TSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815074-B1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | SK CORP (KR) | 2001-10-04 | — | — | EP | disclosed |
| US-5756817-A | TREATMENT OF DISEASES OF CENTRAL NERVOUS SYSTEMS | YUKONG LIMITED (KR) | 1998-05-26 | — | — | US | disclosed |
| US-5705640-A | O-carbamoyl-(d)-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same | YUKONG LIMITED (KR) | 1998-01-06 | — | — | US | disclosed |
| WO-1996024577-A1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1996-08-15 | — | — | WO | disclosed |