Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 16/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 13/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.52 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782326 | 0.83 | CTRB1 (0.52) | KCNA5ALDH1A1 | |
| SCHEMBL7775452 | 0.83 | CTRB1 (0.52) | KCNA5ALDH1A1 | |
| SCHEMBL8717314 | 0.79 | CTRB1 (0.52) | MEN1ALDH1A1KMT2A | |
| SCHEMBL7455452 | 0.79 | CTRB1 (0.54) | KCNA5ALDH1A1 | |
| SCHEMBL7455442 | 0.79 | CTRB1 (0.54) | KCNA5ALDH1A1 | |
| SCHEMBL7780900 | 0.79 | CTRB1 (0.54) | KCNA5ALDH1A1 | |
| SCHEMBL9555974 | 0.79 | HTT (0.59) | KCNA5HPGD | |
| SCHEMBL8669583 | 0.79 | CTRB1 (0.49) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9555799 | 0.78 | HTT (0.58) | KCNA5HPGD | |
| SCHEMBL19050939 | 0.77 | CTSL (0.56) | SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815074-B1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | SK CORP (KR) | 2001-10-04 | — | — | EP | disclosed |
| US-5756817-A | TREATMENT OF DISEASES OF CENTRAL NERVOUS SYSTEMS | YUKONG LIMITED (KR) | 1998-05-26 | — | — | US | disclosed |
| US-5705640-A | O-carbamoyl-(d)-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same | YUKONG LIMITED (KR) | 1998-01-06 | — | — | US | disclosed |
| WO-1996024577-A1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1996-08-15 | — | — | WO | disclosed |