Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 1.00 |
| ▸ | ITGA2B | P08514 | 15/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.61 |
| ▸ | F2 | P00734 | 2/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.61 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.61 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.61 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.56 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122825 | 0.87 | ITGB3 (0.75) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7274743 | 0.85 | ITGB3 (0.74) | ITGB3ITGA2BPRSS1F2 | |
| Hydrochloric Acid SCHEMBL8040370 | 0.85 | ITGB3 (0.73) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7316277 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL8410645 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL8407198 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7315288 | 0.81 | ITGB3 (0.68) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL7291480 | 0.80 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL14922315 | 0.80 | ITGB3 (0.66) | ITGB3ITGA2BENPP2 | |
| SCHEMBL7282886 | 0.78 | ITGB3 (0.65) | ITGB3ITGA2BPRSS1F2PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849261-B1 | Piperazinophenyl- and piperazinophenyloxy-carboxylic acid derivatives as well as processes and intermediates for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2001-10-04 | — | — | EP | claimed |
| EP-0849261-A1 | Piperazinophenyl- and piperazinophenyloxy-carboxylic acid derivatives as well as processes and intermediates for their preparation and medicaments containing these compounds | Solvay Pharmaceuticals GmbH (DE) | 1998-06-24 | — | — | EP | claimed |
| JP-10182624-A | — | — | None | — | — | JP | disclosed |
| EP-0849261-B1 | Piperazinophenyl- and piperazinophenyloxy-carboxylic acid derivatives as well as processes and intermediates for their preparation and medicaments containing these compounds | SOLVAY PHARM GMBH (DE) | 2001-10-04 | — | — | EP | disclosed |
| JP-H10182624-A | PIPERAZINOPHENYL-AND PIPERAZINOPHENYLOXY-CARBOXYLIC ACID DERIVATIVE, ITS PRODUCTION PROCESS, PRODUCTION INTERMEDIATE AND ANTITHROMBOGENIC AND PLATELET AGGREGATION SUPPRESSING AGENT CONTAINING THE DERIVATIVE | SOLVAY PHARMACEUT GMBH | 1998-07-07 | — | — | JP | disclosed |
| EP-0849261-A1 | Piperazinophenyl- and piperazinophenyloxy-carboxylic acid derivatives as well as processes and intermediates for their preparation and medicaments containing these compounds | Solvay Pharmaceuticals GmbH (DE) | 1998-06-24 | — | — | EP | disclosed |