SCHEMBL7777757

SCHEMBL7777757

C=C(C)C(=O)Nc1ccc(S(=O)(=O)NS(=O)(=O)c2cccc3ccccc23)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
LMNA P02545 1/20 0.47
TSHR P16473 1/20 0.46
HTR6 P50406 1/20 0.45
ALDH1A1 P00352 3/20 0.44
TP53 P04637 1/20 0.44
HCRTR1 O43613 1/20 0.42
PFKFB3 Q16875 1/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
NLRP3 Q96P20 1/20 0.41
HDAC1 Q13547 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
PGR P06401 1/20 0.41
F2 P00734 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397689 0.86 TSHR (0.62) HTTMEN1KMT2ALMNATSHR
SCHEMBL7785812 0.83 IDO1 (0.51) MEN1KMT2ALMNAALDH1A1POLB
SCHEMBL396802 0.82 KMT2A (0.70) HTTMEN1KMT2ALMNAALDH1A1
SCHEMBL7782556 0.81 LMNA (0.54) MEN1KMT2ALMNAALDH1A1CYP1A2
SCHEMBL7784534 0.80 HCRTR1 (0.44) HTTMEN1KMT2ALMNATSHR
SCHEMBL7785890 0.78 HCRTR1 (0.51) HTTTSHRHTR6ALDH1A1HCRTR1
SCHEMBL7784361 0.78 IDO1 (0.55) MEN1KMT2ALMNAALDH1A1TP53
SCHEMBL27403636 0.76 RXFP1 (0.51) MEN1KMT2AALDH1A1POLBRXFP1
SCHEMBL8801584 0.76 RECQL (0.57) HTTMEN1KMT2ATSHRHTR6
SCHEMBL27404351 0.75 TDP1 (0.41) HTTLMNATSHRALDH1A1HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671660-B1 Lead-frame forming material FUJI PHOTO FILM CO LTD (JP) 2001-10-17 EP disclosed
US-5670293-A LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING FUJI PHOTO FILM CO., LTD. (JP) 1997-09-23 US disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed