Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 3/20 | 0.48 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785201 | 0.85 | CAMK2D (0.61) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5683201 | 0.83 | CAMK2D (0.50) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5686010 | 0.82 | CAMK2D (0.50) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5682623 | 0.81 | CDK2 (0.56) | CAMK2DPRKCACCNA2CDK2CCNT1 | |
| SCHEMBL5686050 | 0.80 | CAMK2D (0.57) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL7873230 | 0.76 | CDK4 (0.42) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5683170 | 0.76 | CAMK2D (0.52) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5792870 | 0.76 | KDM4E (0.44) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL6865510 | 0.75 | CDK4 (0.41) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL6867156 | 0.74 | CDK4 (0.40) | CAMK2DPRKCBPRKCAPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140070-A1 | TREATMENT OF CONDITIONS WITH A NEED FOR THE INHIBITION OF GSK-3 | SMITHKLINE BEECHAM PLC (GB) | 2001-10-10 | — | — | EP | claimed |
| WO-2000038675-A1 | TREATMENT OF CONDITIONS WITH A NEED FOR THE INHIBITION OF GSK-3 | SMITHKLINE BEECHAM PLC (GB) | 2000-07-06 | — | — | WO | claimed |
| EP-1140070-A1 | TREATMENT OF CONDITIONS WITH A NEED FOR THE INHIBITION OF GSK-3 | SMITHKLINE BEECHAM PLC (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038675-A1 | TREATMENT OF CONDITIONS WITH A NEED FOR THE INHIBITION OF GSK-3 | SMITHKLINE BEECHAM PLC (GB) | 2000-07-06 | — | — | WO | disclosed |