Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 10/20 | 0.42 |
| ▸ | CCND1 | P24385 | 10/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 8/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.42 |
| ▸ | CDK2 | P24941 | 8/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 7/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.42 |
| ▸ | CDK1 | P06493 | 5/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 5/20 | 0.42 |
| ▸ | CAMK2G | Q13555 | 5/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 5/20 | 0.42 |
| ▸ | PRKACA | P17612 | 4/20 | 0.42 |
| ▸ | PRKACG | P22612 | 4/20 | 0.42 |
| ▸ | PRKACB | P22694 | 4/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.42 |
| ▸ | PRKCG | P05129 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865510 | 0.84 | CDK4 (0.41) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL6867156 | 0.83 | CDK4 (0.40) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL6860525 | 0.83 | CDK4 (0.40) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL6867375 | 0.83 | CDK4 (0.40) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL7785201 | 0.79 | CAMK2D (0.61) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL6860161 | 0.78 | CDK4 (0.40) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL5683201 | 0.77 | CAMK2D (0.50) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL5686010 | 0.76 | CAMK2D (0.50) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5553378 | 0.76 | GSK3B (0.48) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL7782574 | 0.76 | CAMK2D (0.48) | CDK4CCND1CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657458-B1 | Protein kinase C inhibitors | LILLY CO ELI (US) | 2001-08-22 | — | — | EP | disclosed |