Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 5/20 | 0.61 |
| ▸ | PRKCB | P05771 | 3/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.44 |
| ▸ | PRKCH | P24723 | 2/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683170 | 0.90 | CAMK2D (0.52) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5686010 | 0.87 | CAMK2D (0.50) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5683201 | 0.86 | CAMK2D (0.50) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5686034 | 0.86 | CAMK2D (0.48) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL7782574 | 0.85 | CAMK2D (0.48) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5686050 | 0.83 | CAMK2D (0.57) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8316483 | 0.81 | CAMK2D (0.51) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL7873230 | 0.79 | CDK4 (0.42) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL20243386 | 0.79 | CAMK2D (0.55) | CAMK2DPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL5792870 | 0.79 | KDM4E (0.44) | CAMK2DPRKCBPRKCAPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140070-A1 | TREATMENT OF CONDITIONS WITH A NEED FOR THE INHIBITION OF GSK-3 | SMITHKLINE BEECHAM PLC (GB) | 2001-10-10 | — | — | EP | claimed |
| WO-2000038675-A1 | TREATMENT OF CONDITIONS WITH A NEED FOR THE INHIBITION OF GSK-3 | SMITHKLINE BEECHAM PLC (GB) | 2000-07-06 | — | — | WO | claimed |
| EP-1140070-A1 | TREATMENT OF CONDITIONS WITH A NEED FOR THE INHIBITION OF GSK-3 | SMITHKLINE BEECHAM PLC (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000038675-A1 | TREATMENT OF CONDITIONS WITH A NEED FOR THE INHIBITION OF GSK-3 | SMITHKLINE BEECHAM PLC (GB) | 2000-07-06 | — | — | WO | disclosed |