Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784376 | 0.86 | HPGD (0.46) | CNR2HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL8070069 | 0.86 | ALDH1A1 (0.46) | CNR2HPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL7218658 | 0.75 | NR4A2 (0.59) | HPGDALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7217500 | 0.72 | ALDH1A1 (0.52) | HPGDALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7782582 | 0.69 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL7839279 | 0.67 | NR4A2 (0.59) | HPGDALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9452783 | 0.67 | KDM4E (0.63) | HPGDALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL29956415 | 0.67 | ALDH1A1 (0.62) | HPGDALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL869550 | 0.65 | BRD4 (0.50) | HPGDALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL30854919 | 0.65 | KDM4E (0.69) | HPGDALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833818-B1 | 3-ACYLINDOLES AS CB2 RECEPTOR AGONISTS | SANOFI SYNTHELABO (FR) | 2001-10-17 | — | — | EP | disclosed |
| US-6013648-A | IMMUNOMODULATORS | SANOFI (FR) | 2000-01-11 | — | — | US | disclosed |
| EP-0833818-A1 | CB 2? RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000860-A1 | CB2 RECEPTOR AGONIST COMPOUNDS | SANOFI (FR) | 1997-01-09 | — | — | WO | disclosed |