SCHEMBL957476

SCHEMBL957476

O=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.62
LMNA P02545 1/20 0.36
CA2 P00918 15/20 0.36
CA1 P00915 14/20 0.36
MMP1 P03956 2/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP8 P22894 2/20 0.36
MMP13 P45452 2/20 0.36
GAA P10253 1/20 0.33
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782672 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL955674 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL7779859 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL536269 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL428315 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL465610 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL953593 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL7779621 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL957654 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
Water SCHEMBL11048628 0.97 THRB (0.59) THRBLMNACA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073712-A Preparation method and application of low-chlorine epoxy resin 杜彪 2022-09-20 CN claimed
CN-118139839-A Process for producing fluorinated polyether 株式会社力森诺科 2024-06-04 CN disclosed
CN-118055920-A Process for producing fluorinated polyether 株式会社力森诺科 2024-05-17 CN disclosed
CN-114790132-B Fluorine-containing aldehyde and preparation method thereof 三明学院 2024-03-22 CN disclosed
CN-115850542-B Perfluoropolymer surfactant and preparation method and application thereof 苏州润邦半导体材料科技有限公司 2023-05-26 CN disclosed
CN-115850542-A Perfluoro polymer surfactant and preparation method and application thereof 苏州润邦半导体材料科技有限公司 2023-03-28 CN disclosed
CN-110770200-B Process for preparing polyfluorinated allyl ethers and compounds related thereto 3M创新有限公司 2022-10-04 CN disclosed
US-20220289785-A1 NOVEL TETRAGALNAC AND PEPTIDE CONTAINING CONJUGATES AND METHODS FOR DELIVERY OF OLIGONUCLEOTIDES BANK OF AMERICA, N.A. 2022-09-15 US disclosed
CN-114790132-A Fluorine-containing aldehyde and preparation method thereof 三明学院 2022-07-26 CN disclosed
US-11292763-B2 Methods of making a polyfluorinated allyl ether and compounds relating to the methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
EP-0935486-A1 AQUEOUS FILM-FORMING FOAM COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-08-18 EP disclosed
WO-1998019988-A1 ALPHA-BRANCHED FLUOROALKYLCARBONYL FLUORIDES AND THEIR DERIVATIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-05-14 WO disclosed
WO-1998019742-A1 AQUEOUS FILM-FORMING FOAM COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-05-14 WO disclosed
US-5466877-A Fluorination with deesterification and alkylation MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-14 US disclosed
WO-1995025082-A1 PROCESS FOR CONVERTING PERFLUORINATED ESTERS TO PERFLUORINATED ACYL FLUORIDES AND/OR KETONES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-09-21 WO disclosed
US-4349650-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-14 US disclosed
US-4292449-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
US-4275225-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-23 US disclosed
US-4273729-A CARBONYL OR SULFONYL FLUORIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
US-4273728-A NITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289785-A1 NOVEL TETRAGALNAC AND PEPTIDE CONTAINING CONJUGATES AND METHODS FOR DELIVERY OF OLIGONUCLEOTIDES GALNT3, CSGALNACT1, FUT6 THRB 254/4885LMNA 1907/4885CA2 3281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.