SCHEMBL955674

SCHEMBL955674

O=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.62
LMNA P02545 1/20 0.36
CA2 P00918 15/20 0.36
CA1 P00915 14/20 0.36
MMP1 P03956 2/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP8 P22894 2/20 0.36
MMP13 P45452 2/20 0.36
GAA P10253 1/20 0.33
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL957476 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL7782672 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL7779859 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL536269 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL428315 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL465610 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL953593 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL7779621 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
SCHEMBL957654 1.00 THRB (0.62) THRBLMNACA2CA1MMP1
Water SCHEMBL11048628 0.97 THRB (0.59) THRBLMNACA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841433-B1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL CO (JP) 2017-06-21 EP disclosed
US-9380782-B2 Tetrazolinone compounds and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-05 US disclosed
EP-2841433-A1 TETRAZOLINONE COMPOUNDS AND ITS USE Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-29 US disclosed
WO-2013162077-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
WO-2012133928-A1 TRIMERIZATION CATALYST AND METHOD FOR PRODUCING 1-HEXENE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 WO disclosed
US-7932330-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-26 US disclosed
US-7872080-B2 Processes for producing a catalyst component for addition polymerization, a catalyst and an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-18 US disclosed
US-20110009579-A1 Processes For Producing A Catalyst Component For Addition Polymerization, A Catalyst And An Addition Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-7592402-B2 Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-22 US disclosed
EP-0757690-A4 ELECTRON-DEFICIENT PORPHYRINS AND PROCESSES AND INTERMEDIATES FOR PREPARING SAME UNIV PENNSYLVANIA (US) 1999-06-16 EP disclosed
US-5856515-A Electron-deficient porphyrins and processes and intermediates for preparing same TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1999-01-05 US disclosed
US-5817830-A Pyrrolic compounds TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-10-06 US disclosed
EP-0821686-A4 NOVEL PORPHYRINS AND PORPHYRIN SYNTHESIS TECHNIQUES UNIV PENNSYLVANIA (US) 1998-04-15 EP disclosed
EP-0825167-A1 COMPOUNDS AND SURFACTANTS ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1998-02-25 EP disclosed
EP-0821686-A1 NOVEL PORPHYRINS AND PORPHYRIN SYNTHESIS TECHNIQUES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-02-04 EP disclosed
EP-0757690-A1 ELECTRON-DEFICIENT PORPHYRINS AND PROCESSES AND INTERMEDIATES FOR PREPARING SAME TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1997-02-12 EP disclosed
US-5599924-A Electron-deficient porphyrins and processes and intermediates for preparing same TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1997-02-04 US disclosed
WO-1996017844-A1 NOVEL PORPHYRINS AND PORPHYRIN SYNTHESIS TECHNIQUES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1996-06-13 WO disclosed
WO-1995029916-A1 ELECTRON-DEFICIENT PORPHYRINS AND PROCESSES AND INTERMEDIATES FOR PREPARING SAME THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1995-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE CBR3, CYP51A1, CYP8B1 THRB 706/4885LMNA 3920/4885CA2 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.