Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782692 | 1.00 | MEN1 (0.45) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL3733758 | 0.83 | MEN1 (0.61) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL3733757 | 0.83 | MEN1 (0.61) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL3729617 | 0.81 | CYP3A4 (0.50) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL3737297 | 0.76 | MEN1 (0.55) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL3735332 | 0.75 | CTSL (0.59) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL3735328 | 0.75 | CTSL (0.59) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL3727263 | 0.74 | CTSL (0.54) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL7669423 | 0.73 | RAB9A (0.42) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL3738178 | 0.73 | MEN1 (0.48) | MEN1KMT2ACTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150956-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047561-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2000-08-17 | — | — | WO | disclosed |