Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8851080 | 0.82 | PRSS1 (0.47) | PRSS1PRSS2PRSS3LMNACA1 | |
| SCHEMBL8985081 | 0.82 | LOXL2 (0.56) | FOLH1 | |
| SCHEMBL1926951 | 0.81 | FOLH1 (0.66) | PRSS1PRSS2PRSS3PLA2G2ACA1 | |
| SCHEMBL14146996 | 0.81 | PRSS1 (0.61) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL271385 | 0.80 | L3MBTL1 (0.52) | CA1CA2CA9KMT2A | |
| SCHEMBL9345509 | 0.80 | MRGPRX4 (0.50) | PTPN1KMT2A | |
| SCHEMBL1375356 | 0.78 | PRSS1 (0.50) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL1375355 | 0.78 | PRSS1 (0.50) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL6201817 | 0.78 | PRSS1 (0.58) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL6190226 | 0.78 | LMNA (0.69) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5279293-A | — | — | None | — | — | JP | disclosed |
| EP-0749973-B1 | Novel bisphosphines as catalysts for asymmetric reactions | BAYER AG (DE) | 2001-11-14 | — | — | EP | disclosed |
| EP-0643065-B1 | Novel bisphosphines for asymetric hydrogenation catalysts | BAYER AG (DE) | 1999-11-10 | — | — | EP | disclosed |
| US-5801261-A | Bisphosphines as catalysts for asymmetric reactions | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-01 | — | — | US | disclosed |
| US-5710339-A | REACTION OF PHOSPHOROUS OXYCHLORIDE WITH 5-BROMO-2-CHLORO ANISOLE AND REACTION WITH GRIGNARD REAGENT, LITHIUM AMIDE AND IODINE FOR DIMERIZATION THEN COMPLEXING | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0529444-B1 | 2-Arylpropenic acids and their utilisation in the preparation of 5-ketoprofen | BAYER AG (DE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0749973-A1 | Novel bisphosphines as catalysts for asymmetric reactions | BAYER AG (DE) | 1996-12-27 | — | — | EP | disclosed |
| US-5510503-A | Bisphosphines for asymmetric hydrogenation catalysts | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| EP-0643065-A1 | Novel bisphosphines for asymetric hydrogenation catalysts | BAYER AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| US-5362907-A | Intermediates and their use in the preparation of s-ketoprofen | BAYER AKTIENGESELLSCHAFT (DE) | 1994-11-08 | — | — | US | disclosed |
| JP-H05279293-A | INTERMEDIATE AND ITS USE IN PRODUCTION OF S-KETOPROFEN | BAYER AG | 1993-10-26 | — | — | JP | disclosed |
| EP-0529444-A2 | 2-Arylpropenic acids and their utilisation in the preparation of 5-ketoprofen | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |