SCHEMBL7782929

SCHEMBL7782929

CC(C)CC(C)(OOOC(=O)C(=O)OCl)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GRIN2D O15399 2/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32
GRIN2B Q13224 2/20 0.32
GRIN2C Q14957 2/20 0.32
OPRM1 P35372 2/20 0.32
CACNA1F O60840 1/20 0.32
ABCB1 P08183 1/20 0.32
CYP2B6 P20813 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
CACNA1D Q01668 1/20 0.32
CACNA1S Q13698 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL481608 0.76 MAPK1 (0.46) CYP2C19HIF1AGAASMN1; SMN2GRIN2D
SCHEMBL481584 0.72 MAPK1 (0.42) CYP2C19HIF1AGAASMN1; SMN2GRIN2D
SCHEMBL4663349 0.71 ALDH1A1 (0.51) CYP2C19GAASMN1; SMN2ALDH1A1TDP1
SCHEMBL25015318 0.71 KCNN4 (0.38) KCNH2CYP2C19HIF1AGAASMN1; SMN2
SCHEMBL481266 0.70 MAPK1 (0.61) KCNH2CYP2C19HIF1AGAASMN1; SMN2
SCHEMBL362549 0.70 ALDH1A1 (0.50) KCNH2CYP2C19HIF1AGAASMN1; SMN2
SCHEMBL28558462 0.70 CYP2D6 (0.45) KCNH2CYP2C19HIF1AGAASMN1; SMN2
SCHEMBL5491740 0.68 ALDH1A1 (0.38) HIF1ASMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL873678 0.66 CYP2C19 (0.46) CYP2C19HIF1AGAASMN1; SMN2GRIN2D
SCHEMBL7791408 0.66 TSHR (0.31) ALDH1A1TDP1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850928-B1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ATOFINA CHEM INC (US) 2001-10-31 EP disclosed
EP-0850929-B1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ATOFINA CHEM INC (US) 2001-06-27 EP disclosed
US-5981787-A INITIATORS FOR POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS AND FOR CURING OF UNSATURATED POLYESTER RESINS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-11-09 US disclosed
US-5837782-A POLYMERIZATION CATALYST ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-11-17 US disclosed
EP-0850929-A1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed
EP-0850928-A1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed