SCHEMBL28558462

SCHEMBL28558462

CC(C)CC(C)(OC(N)=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.45
CYP1A2 P05177 2/20 0.45
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.43
KIF11 P52732 3/20 0.40
KCNH2 Q12809 2/20 0.39
LMNA P02545 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
KDM4E B2RXH2 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
GRIN2D O15399 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2B Q13224 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2283147 0.81 MAPT (0.48) CYP2D6CYP1A2MAPTKMT2ACYP2C19
SCHEMBL27596019 0.81 MAPT (0.48) CYP2D6CYP1A2MAPTKMT2ACYP2C19
SCHEMBL29118559 0.81 KMT2A (0.48) CYP2D6CYP1A2MAPTKMT2ACYP2C19
SCHEMBL16028069 0.80 MAPT (0.47) CYP2D6CYP1A2MAPTKMT2ACYP2C19
SCHEMBL10518614 0.80 MAPT (0.47) CYP2D6CYP1A2MAPTKMT2ACYP2C19
SCHEMBL29118554 0.79 MAPT (0.46) CYP2D6CYP1A2MAPTKMT2ACYP2C19
SCHEMBL7619909 0.79 SLC6A2 (0.48) CYP2D6CYP1A2MAPTKMT2ACYP2C19
SCHEMBL27838486 0.79 MAPT (0.46) CYP2D6CYP1A2MAPTKMT2ACYP2C19
SCHEMBL31220603 0.79 MAPT (0.37) CYP2D6CYP1A2MAPTKMT2ACYP2C19
SCHEMBL15269001 0.78 ALDH1A1 (0.45) MAPTKMT2AKIF11LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112714764-A 3- (2-thienyl) -5- (trifluoromethyl) -1,2, 4-oxadiazole derivatives as agrochemical fungicides 先正达农作物保护股份公司 2021-04-27 CN disclosed