Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | IDH2 | P48735 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7781124 | 0.99 | THRB (0.61) | THRBEGFRERBB4AURKAGPR52 | |
| SCHEMBL7781150 | 0.88 | THRB (0.55) | THRBEGFRERBB4AURKAKDM4E | |
| SCHEMBL7780162 | 0.87 | GPR52 (0.48) | THRBEGFRERBB4AURKAGPR52 | |
| Hydrochloric Acid SCHEMBL7776099 | 0.86 | GPR52 (0.48) | THRBEGFRERBB4AURKAGPR52 | |
| SCHEMBL7780190 | 0.86 | THRB (0.47) | THRBEGFRERBB4GPR52TNNI3K | |
| Hydrochloric Acid SCHEMBL7783011 | 0.85 | THRB (0.46) | THRBEGFRERBB4GPR52TNNI3K | |
| SCHEMBL30141460 | 0.84 | THRB (0.65) | THRBEGFRERBB4AURKAGPR52 | |
| SCHEMBL1387447 | 0.83 | THRB (0.80) | THRBEGFRERBB4AURKAKDM4E | |
| SCHEMBL374332 | 0.80 | THRB (0.74) | THRBEGFRERBB4AURKAKDM4E | |
| SCHEMBL7776064 | 0.78 | HTR2B (0.46) | GPR52MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972770-B1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | BASF AG (DE) | 2001-09-19 | — | — | EP | claimed |
| US-6281219-B1 | 4,6-BIS-ARYL-PYRIMIDINES WHEREIN THE AROMATIC GROUPS ARE ATTACHED VIA TWO LINKING GROUPS WHICH ARE DIFFERENT FROM ONE ANOTHER. | AMERICAN CYANAMID CO. | 2001-08-28 | — | — | US | claimed |
| EP-0972770-A1 | Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof | American Cyanamid Company (US) | 2000-01-19 | — | — | EP | claimed |