Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779341 | 0.72 | KMT2A (0.36) | ALDH1A1MAPTITGA4 | |
| SCHEMBL28330586 | 0.69 | — | — | |
| SCHEMBL28846712 | 0.67 | — | — | |
| SCHEMBL28755973 | 0.66 | — | — | |
| SCHEMBL29639106 | 0.65 | HTR5A (0.35) | — | |
| SCHEMBL926937 | 0.65 | HTR5A (0.35) | — | |
| SCHEMBL5423113 | 0.63 | — | — | |
| SCHEMBL4624447 | 0.63 | MEN1 (0.37) | ALDH1A1MAPTITGA4 | |
| Hydrochloric Acid SCHEMBL30881482 | 0.63 | HTR5A (0.34) | — | |
| Iodide SCHEMBL29258426 | 0.63 | HTR5A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552329-B1 | METHYLEN-OXINDOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN SPA (IT) | 2001-10-04 | — | — | EP | disclosed |
| US-5409949-A | Methylen-oxindole derivatives compositions and tyrosine kinase inhibition therewith | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-04-25 | — | — | US | disclosed |
| EP-0552329-A1 | METHYLEN-OXINDOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |
| EP-0525472-A2 | Methylen-oxindole derivatives and process for their preparation | PHARMACIA S.p.A. (IT) | 1993-02-03 | — | — | EP | disclosed |
| WO-1993001182-A1 | METHYLEN-OXINDOLE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA SRL (IT) | 1993-01-21 | — | — | WO | disclosed |