Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784902 | 0.85 | SMN1; SMN2 (0.34) | PDE7AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL7778137 | 0.82 | NR1H2 (0.31) | — | |
| SCHEMBL7783639 | 0.76 | VCAM1 (0.39) | MAPTKCNMA1ALDH1A1POLBMAPK1 | |
| SCHEMBL7786263 | 0.72 | PTGS1 (0.39) | MAPTPOLBMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL7783612 | 0.72 | MAPK1 (0.37) | MAPTKCNMA1ALDH1A1POLBMAPK1 | |
| SCHEMBL8532395 | 0.71 | KDM4E (0.38) | MAPTALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL8664414 | 0.70 | KDM4E (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28752946 | 0.70 | KDM4E (0.37) | MAPTALDH1A1TDP1CYP1A2CYP2C9 | |
| SCHEMBL7782978 | 0.70 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL7782597 | 0.68 | NPSR1 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |