Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782597 | 0.95 | NPSR1 (0.42) | PTGS1PTGS2PPARGHTTPTGDR2 | |
| SCHEMBL8532395 | 0.78 | KDM4E (0.38) | MAPTHTTTDP1LMNAKDM4E | |
| SCHEMBL8664414 | 0.77 | KDM4E (0.31) | PTGS1PTGS2HTTKDM4E | |
| SCHEMBL7784780 | 0.77 | PTGS1 (0.37) | PTGS1PTGS2CHRNA7MAPTHTT | |
| Hydrochloric Acid SCHEMBL28752946 | 0.77 | KDM4E (0.37) | MAPTHTTTDP1LMNAKDM4E | |
| SCHEMBL7782978 | 0.76 | KDM4E (0.31) | PTGS1PTGS2KDM4E | |
| SCHEMBL7784902 | 0.73 | SMN1; SMN2 (0.34) | MAPTHTTSMN1; SMN2TDP1PTGDR2 | |
| SCHEMBL7782871 | 0.73 | ALDH1A1 (0.38) | PTGS1PTGS2PPARGCHRNA7TDP1 | |
| SCHEMBL7782997 | 0.72 | PDE7A (0.37) | MAPTSMN1; SMN2TDP1POLBLMNA | |
| SCHEMBL7784924 | 0.72 | MAPT (0.39) | CHRNA7MAPTHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |