Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778137 | 0.86 | NR1H2 (0.31) | NR1H2NR1H3TP53 | |
| SCHEMBL7782997 | 0.85 | PDE7A (0.37) | SMN1; SMN2MAPTNPSR1LMNATDP1 | |
| SCHEMBL7778342 | 0.78 | PTGDR2 (0.33) | SMN1; SMN2MAPTXBP1HTTNPSR1 | |
| SCHEMBL7782597 | 0.77 | NPSR1 (0.42) | HTTNPSR1LMNAPTGDR2MEN1 | |
| SCHEMBL7782854 | 0.77 | PTGDR2 (0.32) | SMN1; SMN2MAPTXBP1HTTNPSR1 | |
| Hydrochloric Acid SCHEMBL28752946 | 0.75 | KDM4E (0.37) | MAPTHTTLMNATDP1MEN1 | |
| SCHEMBL8664414 | 0.73 | KDM4E (0.31) | HTTTP53 | |
| SCHEMBL7786263 | 0.73 | PTGS1 (0.39) | SMN1; SMN2MAPTHTTNPSR1LMNA | |
| SCHEMBL7782978 | 0.72 | KDM4E (0.31) | TP53 | |
| SCHEMBL7784793 | 0.72 | KDM4E (0.44) | MAPTNPSR1TDP1PTGDR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |