Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | PDE1A | P54750 | 4/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860525 | 0.85 | PDE5A (0.42) | MEN1KMT2ACCNB2CDK1CCNB1 | |
| SCHEMBL7783054 | 0.85 | PDE5A (0.42) | MEN1KMT2ACCNB2CDK1CCNB1 | |
| SCHEMBL7781023 | 0.84 | PDE5A (0.43) | CASP6MEN1KMT2ACCNB2CDK1 | |
| SCHEMBL7783094 | 0.82 | PDE5A (0.35) | MEN1KMT2APDE5APDE1APDE1B | |
| SCHEMBL7776481 | 0.81 | PDE5A (0.43) | CASP6MEN1KMT2ACCNB2CDK1 | |
| SCHEMBL7781030 | 0.79 | PDE5A (0.48) | PDE5APDE1APDE1BPDE1CPDE4A | |
| SCHEMBL7783337 | 0.79 | CTSK (0.46) | MEN1KMT2APDE5APDE1APDE1B | |
| SCHEMBL2484816 | 0.78 | ALDH1A1 (0.35) | MEN1KMT2ACCNB2CDK1CCNB1 | |
| SCHEMBL1961907 | 0.78 | MEN1 (0.35) | MEN1KMT2ACCNB2CDK1CCNB1 | |
| SCHEMBL7776470 | 0.77 | PDE5A (0.48) | CASP6MEN1KMT2APDE5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775141-B1 | PHENYL XANTHINE DERIVATIVES | WELLCOME FOUND (GB) | 2001-09-26 | — | — | EP | disclosed |
| US-5776940-A | COMPOUNDS FOR TREATMENT OF SEPTIC SHOCK, ANTIINFLAMMATORY AND ANTIALLERGENS | GLAXO WELLCOME INC. (US) | 1998-07-07 | — | — | US | disclosed |