Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155989 | 0.92 | DRD2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6764904 | 0.88 | KDM1A (0.37) | CYP19A1CYP11B1CYP11B2KDM1A | |
| Hydrochloric Acid SCHEMBL1277119 | 0.72 | CYP19A1 (0.31) | CYP19A1CYP11B1CYP11B2KDM1A | |
| Hydrochloric Acid SCHEMBL215791 | 0.72 | CYP19A1 (0.31) | CYP19A1CYP11B1CYP11B2KDM1A | |
| Hydrochloric Acid SCHEMBL218231 | 0.72 | CYP19A1 (0.31) | CYP19A1CYP11B1CYP11B2KDM1A | |
| SCHEMBL7696567 | 0.71 | KDM1A (0.32) | KDM1A | |
| SCHEMBL5081798 | 0.69 | KDM1A (0.31) | KDM1A | |
| Hydrochloric Acid SCHEMBL7582802 | 0.69 | LMNA (0.31) | — | |
| Hydrochloric Acid SCHEMBL4078684 | 0.69 | HTR2A (0.31) | — | |
| Hydrochloric Acid SCHEMBL7783229 | 0.69 | CYP11B1 (0.31) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1136122-A1 | TRANSITION METAL CATALYSTS AND PROCESSES FOR PRODUCING $g(a)-OLEFIN AND VINYL COMPOUND POLYMER | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2001-09-26 | — | — | EP | disclosed |