Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270126 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL31424902 | 0.84 | ALDH1A1 (0.61) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL10628482 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL1477561 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8103680 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL3202573 | 0.80 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL7782688 | 0.78 | MAPK1 (0.47) | ALDH1A1TSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3590165 | 0.78 | CYP1A2 (0.54) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL5185195 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDKMT2AMEN1 | |
| SCHEMBL5186181 | 0.77 | ALDH1A1 (0.74) | ALDH1A1TSHRHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-0901501-B1 | NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-6153744-A | LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON A DNA CHIP | WOLFGANG PFLEIDERER (DE) | 2000-11-28 | — | — | US | disclosed |
| EP-0901501-A1 | NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS | Pfleiderer, Wolfgang (DE) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997044345-A1 | NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 1997-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | ALDH1A1 1904/4885TSHR 1731/4885HPGD 2117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.