SCHEMBL270126

SCHEMBL270126

O=[N+]([O-])c1ccccc1CS(=O)(=O)Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
TSHR P16473 1/20 0.61
HPGD P15428 1/20 0.51
CA12 O43570 1/20 0.50
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46
NPC1 O15118 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31424902 1.00 ALDH1A1 (0.61) ALDH1A1TSHRHPGDCA12KMT2A
Hydrochloric Acid SCHEMBL8103680 0.98 ALDH1A1 (0.59) ALDH1A1TSHRHPGDCA12KMT2A
SCHEMBL6895483 0.91 KMT2A (0.53) ALDH1A1TSHRHPGDCA12KMT2A
SCHEMBL28613032 0.85 ALDH1A1 (0.60) ALDH1A1TSHRHPGDCA12KMT2A
SCHEMBL4373604 0.84 ALDH1A1 (0.47) ALDH1A1TSHRHPGDCA12KMT2A
SCHEMBL7783353 0.84 ALDH1A1 (0.59) ALDH1A1TSHRHPGDCA12KMT2A
SCHEMBL31628174 0.83 ALDH1A1 (0.58) ALDH1A1TSHRHPGDCA12KMT2A
SCHEMBL9826058 0.83 ALDH1A1 (0.58) ALDH1A1TSHRHPGDCA12KMT2A
SCHEMBL27859393 0.82 ALDH1A1 (0.58) ALDH1A1TSHRHPGDCA12KMT2A
SCHEMBL448648 0.81 ALDH1A1 (0.56) ALDH1A1TSHRHPGDCA12KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3180307-A1 PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES Seegpharm SA (CH) 2017-06-21 EP claimed
WO-2016016321-A1 PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES SEEGPHARM SA (CH) 2016-02-04 WO claimed
WO-2000006525-A9 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS HARVARD COLLEGE (US) 2000-04-20 WO claimed
WO-2000006525-A2 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-02-10 WO claimed
US-12583832-B2 Cannabinoid analogs, formulations, and methods of use NALU BIO, INC. (US) 2026-03-24 US disclosed
US-12576029-B2 Noncompetitive receptor-targeted vaccine delivery to plasmacytoid dendritic cells WASHINGTON UNIVERSITY (US) 2026-03-17 US disclosed
US-20260001856-A1 CANNABINOID ANALOGS, FORMULATIONS, AND METHODS OF USE NALU BIO, INC. 2026-01-01 US disclosed
US-20250340568-A1 SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION VERTEX PHARMA (US) 2025-11-06 US disclosed
US-20250320226-A1 METHODS OF PREPARING AND CRYSTALLINE FORMS OF (6A,12A)-17-AMINO-12-METHYL-6,15-BIS(TRIFLUOROMETHYL)-13,19-DIOXA-3,4,18-TRIAZATRICYCLO[12.3.1.12,5]NONADECA-1(18),2,4,14,16-PENTAEN-6-OL VERTEX PHARMA (US) 2025-10-16 US disclosed
US-20250270181-A1 SYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS, AND RELATED COMPOUNDS, FORMULATIONS, AND METHODS OF USE NALU BIO, INC. 2025-08-28 US disclosed
US-12264143-B2 Synthesis of cannabinoids and cannabinoid precursors, and related compounds, formulations, and methods of use NALU BIO, INC. (US) 2025-04-01 US disclosed
CN-119731183-A Solid forms of macrocyclic compounds as CFTR modulators and their preparation 弗特克斯药品有限公司 2025-03-28 CN disclosed
WO-1994018165-A1 SULFONAMIDE COMPOUNDS AS OPIOID K-RECEPTOR AGONISTS PFIZER INC. (US) 1994-08-18 WO disclosed
EP-0051466-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-01-09 EP disclosed
EP-0044209-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-31 EP disclosed
US-4454334-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-06-12 US disclosed
US-4420325-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS & COMPANY (US) 1983-12-13 US disclosed
US-4397679-A PREEMERGENCE, POSTEMERGENCE, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-08-09 US disclosed
EP-0051466-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-12 EP disclosed
EP-0044209-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12264143-B2 Synthesis of cannabinoids and cannabinoid precursors, and related compounds, formulations, and methods of use CNR2, CNR1, HMBS ALDH1A1 3324/4885TSHR 2985/4885HPGD 130/4885
US-12576029-B2 Noncompetitive receptor-targeted vaccine delivery to plasmacytoid dendritic cells DGKG, PHOSPHO1, TLR3 ALDH1A1 4639/4885TSHR 1112/4885HPGD 2093/4885
US-20250270181-A1 SYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS, AND RELATED COMPOUNDS, FORMULATIONS, AND METHODS OF USE CNR2, CNR1, HMBS ALDH1A1 3324/4885TSHR 2985/4885HPGD 130/4885
US-20250340568-A1 SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION CFTR, SLC26A4, PKD1 ALDH1A1 2754/4885TSHR 2266/4885HPGD 941/4885
US-12583832-B2 Cannabinoid analogs, formulations, and methods of use CNR1, CNR2, CYP8B1 ALDH1A1 1980/4885TSHR 2821/4885HPGD 244/4885
US-20250320226-A1 METHODS OF PREPARING AND CRYSTALLINE FORMS OF (6A,12A)-17-AMINO-12-METHYL-6,15-BIS(TRIFLUOROMETHYL)-13,19-DIOXA-3,4,18-TRIAZATRICYCLO[12.3.1.12,5]NONADECA-1(18),2,4,14,16-PENTAEN-6-OL CFTR, PKD1, AQP1 ALDH1A1 938/4885TSHR 3531/4885HPGD 578/4885
US-20260001856-A1 CANNABINOID ANALOGS, FORMULATIONS, AND METHODS OF USE CNR2, CNR1, CTNND1 ALDH1A1 3757/4885TSHR 1657/4885HPGD 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.