Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369743 | 1.00 | HIF1A (0.41) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL29647890 | 0.93 | HIF1A (0.40) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL7786380 | 0.93 | HIF1A (0.40) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL7786379 | 0.93 | HIF1A (0.40) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL29377786 | 0.92 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL675260 | 0.92 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL18977 | 0.92 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL17701174 | 0.91 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL12704698 | 0.91 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL4648199 | 0.89 | TAS2R14 (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840726-B1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | SYNGENTA LTD (GB) | 2001-10-10 | — | — | EP | disclosed |
| US-6015905-A | REACTING OXY-METAL DERIVATIVE OF A DISUBSTITUTED PYRIDINE WITH METHYL ESTER OF PHENYLACETIC ACID(WHICH ALSO HAS ALKYL SUBSTITUENT ON RING) YIELDS INTERMEDIATE FOR PREPARATION OF AGRICULTURAL FUNGICIDES | ZENECA LIMITED | 2000-01-18 | — | — | US | disclosed |