Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369743 | 0.91 | HIF1A (0.41) | HIF1AP2RX7TAS2R14HCRTR1HCRTR2 | |
| SCHEMBL7783632 | 0.91 | HIF1A (0.41) | HIF1AP2RX7TAS2R14HCRTR1HCRTR2 | |
| SCHEMBL29647890 | 0.90 | HIF1A (0.40) | HIF1AP2RX7TAS2R14HCRTR1HCRTR2 | |
| SCHEMBL7786380 | 0.90 | HIF1A (0.40) | HIF1AP2RX7TAS2R14HCRTR1HCRTR2 | |
| SCHEMBL7786379 | 0.90 | HIF1A (0.40) | HIF1AP2RX7TAS2R14HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL18977 | 0.89 | HIF1A (0.39) | HIF1AP2RX7TAS2R14HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL675260 | 0.89 | HIF1A (0.39) | HIF1AP2RX7TAS2R14HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL29377786 | 0.89 | HIF1A (0.39) | HIF1AP2RX7TAS2R14HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL17701174 | 0.88 | HIF1A (0.39) | HIF1AP2RX7TAS2R14HCRTR1HCRTR2 | |
| SCHEMBL17230111 | 0.85 | GABRA5 (0.38) | HIF1APDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2311321-A2 | Insecticide on the basis of neonicotinoids and selected strobilurins | Bayer CropScience AG (DE) | 2011-04-20 | — | — | EP | disclosed |
| EP-2301354-A2 | Insecticide on the basis of neonicotinoids and selected strobilurins | Bayer CropScience AG (DE) | 2011-03-30 | — | — | EP | disclosed |
| EP-2301355-A2 | Insecticides based on nicotinoides and specific strobilurines | Bayer CropScience AG (DE) | 2011-03-30 | — | — | EP | disclosed |
| EP-2127523-A2 | Insecticide on the basis of neonicotinoids and selected strobilurins | Bayer CropScience AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| US-20080274882-A1 | Insecticides Based on Selected Neonicotinoids and Strobilurins | BAYER CROPSCIENCE AG (DE) | 2008-11-06 | — | — | US | disclosed |
| EP-1929868-A2 | Fungicidal mixtures based on prothioconazole and a strobilurin derivative | BASF SE (DE) | 2008-06-11 | — | — | EP | disclosed |
| EP-1642499-B1 | Fungicidal mixtures based on prothioconazole and picoxystrobin | BASF SE (DE) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274882-A1 | Insecticides Based on Selected Neonicotinoids and Strobilurins | STMN2, STMN1, DDX6 | HIF1A 4622/4885P2RX7 90/4885TAS2R14 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.