Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783632 | 1.00 | HIF1A (0.41) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL29647890 | 0.93 | HIF1A (0.40) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL7786380 | 0.93 | HIF1A (0.40) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL7786379 | 0.93 | HIF1A (0.40) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL29377786 | 0.92 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL675260 | 0.92 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL18977 | 0.92 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| Picoxystrobin SCHEMBL17701174 | 0.91 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL12704698 | 0.91 | HIF1A (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 | |
| SCHEMBL4648199 | 0.89 | TAS2R14 (0.39) | HIF1ATAS2R14P2RX7HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186861-B2 | Z-substituted acrylamides, methods for production thereof and agents comprising the same | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-06 | — | — | US | disclosed |
| US-7094894-B2 | Fungicidal triazolopyrimidines, method for the production thereof, use thereof for controlling harmful fungi, and agents containing said fungicidal triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-22 | — | — | US | disclosed |
| US-20060135538-A1 | 7-(R)-aminotriazolopyrimidines, their preparation and their use for controlling phytopathogenic fungi | BLASCO JORDI TORMO I | 2006-06-22 | — | — | US | disclosed |
| US-20050256138-A1 | Fungicidal triazolopyrimidines, method for the production thereof, use thereof for controlling harmful fungi, and agents containing said fungicidal triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-17 | — | — | US | disclosed |
| US-20050107619-A1 | Z-substituted acrylamides, methods for production thereof and agents comprising the same | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | US | disclosed |
| US-6855718-B2 | 7-(r)-aminotriazolopyrimidines, the production thereof and use of the same for combatting phytopathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-15 | — | — | US | disclosed |
| US-6767923-B2 | Benzhydryl derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2004-07-27 | — | — | US | disclosed |
| US-20040110771-A1 | 7-(r)-aminotriazolopyrimidines, the production thereof and use of the same for combatting phytopathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
| US-20040058938-A1 | Use of substituted imidazoazines, novel imidazoazines, methods for the production thereof, and agents containing these compounds | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | US | disclosed |
| US-20030207938-A1 | Such as 5-bromo-6,6'-dimethyl-2,2',3',4'-tetramethoxybenz-hydryl alcohol for controlling harmful phytopathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135538-A1 | 7-(R)-aminotriazolopyrimidines, their preparation and their use for controlling phytopathogenic fungi | CBR3, DPM1, ERG28 | HIF1A 2643/4885TAS2R14 3094/4885P2RX7 374/4885 |
| US-20040110771-A1 | 7-(r)-aminotriazolopyrimidines, the production thereof and use of the same for combatting phytopathogenic fungi | CBR1, CBR3, DPM1 | HIF1A 1489/4885TAS2R14 4023/4885P2RX7 907/4885 |
| US-20030207938-A1 | Such as 5-bromo-6,6'-dimethyl-2,2',3',4'-tetramethoxybenz-hydryl alcohol for controlling harmful phytopathogenic fungi | CBR1, CBR3, ADH5 | HIF1A 701/4885TAS2R14 1921/4885P2RX7 4715/4885 |
| US-20050256138-A1 | Fungicidal triazolopyrimidines, method for the production thereof, use thereof for controlling harmful fungi, and agents containing said fungicidal triazolopyrimidines | CBR1, CBR3, DPM1 | HIF1A 3119/4885TAS2R14 4413/4885P2RX7 325/4885 |
| US-20050107619-A1 | Z-substituted acrylamides, methods for production thereof and agents comprising the same | AOC2, AZI2, ZYX | HIF1A 1460/4885TAS2R14 2230/4885P2RX7 1170/4885 |
| US-20040058938-A1 | Use of substituted imidazoazines, novel imidazoazines, methods for the production thereof, and agents containing these compounds | CBR3, CBR1, HCCS | HIF1A 1229/4885TAS2R14 2953/4885P2RX7 2190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.