Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645473 | 0.83 | FAAH (0.49) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7685932 | 0.83 | FAAH (0.49) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL182927 | 0.83 | FAAH (0.49) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL12935660 | 0.81 | ZDHHC7 (0.41) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL15908076 | 0.79 | CTSK (0.40) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL1840893 | 0.78 | GPR84 (0.48) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL1836400 | 0.78 | GPR84 (0.48) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL1835822 | 0.78 | GPR84 (0.48) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL1839748 | 0.78 | GPR84 (0.48) | GPR84FFAR1ZDHHC7MAPTLCK | |
| SCHEMBL1839668 | 0.78 | GPR84 (0.48) | GPR84FFAR1ZDHHC7MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251946-B1 | SATURATED OR UNSATURATED BRANCHED FATTY ACID CONTAINING LIPID ESTER OR FATTY ACID AMIDE TO TREAT CENTRAL NERVOUS SYSTEM DISORDERS, INCLUDING EPILEPSY, MIGRAINES, CHRONIC PAIN AND BIPOLAR DISORDERS | D-PHARM LTD. (IL) | 2001-06-26 | — | — | US | disclosed |